TRD 3 – INTRAOPERATIVE DEVICES

An Intraoperative needle guidance system for prostate biopsy that models needle deflection and derives optimal insertion paths for in-bore MRI-guided prostate interventions.

An augmented reality guided navigation system for thoracoscopic lung surgery with compensation for lung deformation.

Implantable microdevices with integrated retrievability for difficult-to-access tissues, such as the brain.

Bhagavatula SK, Panikkanvalappil SR, Tokuda J, Levesque V, Tatarova Z, Liu G, Markert JE, Jonas O. Superparamagnetic Iron Oxide Nanoparticle Enhanced Percutaneous Microwave Ablation: Ex-Vivo Characterization Using Magnetic Resonance Thermometry. Med Phys. 2024 Mar 21. PMID: 38513254.

Bartholomew RA, Zhou H, Boreel M, Suresh K, Gupta S, Mitchell MB, Hong C, Lee SE, Smith TR, Guenette JP, Corrales CE, Jagadeesan J. Surgical Navigation in the Anterior Skull Base Using 3-Dimensional Endoscopy and Surface Reconstruction. JAMA Otolaryngol Head Neck Surg. 2024 Mar 7. PMID: 38451508.

Ben-Shlomo N, Rahimi A, Abunimer AM, Guenette JP, Juliano AF, Starr JR, Jayender J, Corrales CE. Inner Ear Breaches from Vestibular Schwannoma Surgery: Revisiting the Incidence of Otologic Injury from Retrosigmoid and Middle Cranial Fossa Approaches. Otol Neurotol. 2024 Mar 1;45(3):311-318. PMID: 38238921. PMC10922915.

Ben-Shlomo N, Jayender J, Guenette JP, Corrales CE. Iatrogenic Inner Ear Dehiscence Associated With Lateral Skull Base Surgery: A Systematic Analysis of Drilling Injuries and Their Causal Factors. Acta Neurochir (Wien). 2023 Oct;165(10):2969-2977. PMID: 37430067. PMC10905369.

Peruzzi P, Dominas C, Fell G, Bernstock JD, Blitz S, Mazzetti D, Zdioruk M, Dawood HY, Triggs DV, Ahn SW, Bhagavatula SK, Davidson SM, Tatarova Z, Pannell M, Truman K, Ball A, Gold MP, Pister V, Fraenkel E, Chiocca EA, Ligon KL, Wen PY, Jonas O. Intratumoral Drug-releasing Microdevices Allow in situ High-throughput Pharmaco Phenotyping in Patients with Gliomas. Sci Transl Med. 2023 Sep 6;15(712):eadi0069. PMID: 37672566. PMC10754230.

Burch EA, Bhagavatula SK, Malone FE, Reichert RR, Tuncali K, Levesque VM, Lan Z, Sticka WT, Shyn PB. Tumor and Ablation Margin Visibility during Cryoablation of Musculoskeletal Tumors: Comparing Intraprocedural PET/CT Images with CT-Only Images. J Vasc Interv Radiol. 2023 Aug;34(8):1311-8. PMID: 37028704. PMC10506080.

Moreira P, Tuncali K, Tempany CM, Tokuda J. The Impact of Placement Errors on the Tumor Coverage in MRI-Guided Focal Cryoablation of Prostate Cancer. Acad Radiol. 2021 Jun;28(6):841-48. PMID: 32863151. PMC7910318.

Moreira P, Grimble J, Bernardes MC, Iftimia N, Levesque VM, Foley L, Tuncali K, Tokuda J, Park J. Motorized Template for MRI-Guided Focal Cryoablation of Prostate Cancer. IEEE Trans Med Robot Bionics. 2023 May;5(2):335-42. PMID: 37312886. PMC10259684.

Bernardes MC, Moreira P, Mareschal L, Tempany C, Tuncali K, Hata N, Tokuda J. Data-driven Adaptive Needle Insertion Assist for Transperineal Prostate Interventions. Phys Med Biol. 2023 May 15;68(10). PMID: 37080237. PMC10249778.

Kobayashi S, King F, Hata N. Automatic Segmentation of Prostate and Extracapsular Structures in MRI to Predict Needle Deflection in Percutaneous Prostate Intervention. Int J Comput Assist Radiol Surg. 2023 Mar;18(3):449-60. PMID: 36152168. PMC9974805.