TRD 1 – IMAGING CANCER HETEROGENEITY

Turkbey B, Huisman H, Fedorov A, Macura KJ, Margolis DJ, Panebianco V, Oto A, Schoots IG, Siddiqui MM, Moore CM, Rouvière O, Bittencourt LK, Padhani AR, Tempany CM, Haider MA. Requirements for AI Development and Reporting for MRI Prostate Cancer Detection in Biopsy-Naive Men: PI-RADS Steering Committee, Version 1.0. Radiology. 2025 Apr;315(1):e240140. PMID: 40232134.

Rainer Q, Tuncali K, Ahn W, Santa FV, Hirsch M, Bhagavatula S, Masaki F, Young CT, Marlin C, Martin S, Matthew DU, De Carvalho F, Dominas CA, Stone BV, Tempany C, Jonas O, Kibel AS, Hata N. Feasibility of MRI-Guided Transperineal Implantation of Microdevices for Drug Delivery and Response Assessment in Prostate Cancer. J Magn Reson Imaging. 2025 Apr 11. PMID: 40213929.

Lee EQ, Alexander BM, Romo CG, Supko JG, Agar NYR, Talebi Z, Ahluwalia MS, Desai AS, Dietrich J, Kaley TJ, Peereboom DM, Gantchev J, Baquer G, Santagata S, Takebe N, Desideri S, Fisher JD, Sims M, Ye X, Ligon KL, Nabors LB, Grossman SA, Wen PY. Phase I Study of Adavosertib with Radiotherapy and Temozolomide in Newly Diagnosed Glioblastoma and Intratumoral Drug Levels in Recurrent Glioblastoma. Clin Cancer Res. 2025 Mar 17;31(6):983-992. PMID: 39820282. PMC11913579.

Rendo V, Lee EQ, Bossi C, Khuu N, Rudek MA, Pal S, Azazmeh N, Rashid R, Lin JR, Cusick M, Reynolds ARN, Fassinou ACR, Ayoub G, Malinowski S, Lapinskas E, Pisano W, Jeang J, Stopka SA, Regan MS, Spetz J, Desai A, Lieberman F, Palanichamy K, Fisher JD, Pelton K, Huang RY, Sarosiek KA, Nabors LB, Holdhoff M, Danda N, Strowd R, Desideri S, Walbert T, Ye X, Chakravarti A, Sorger PK, Santagata S, Agar NYR, Grossman SA, Alexander BM, Wen PY, Ligon KL, Beroukhim R. A Window-of-Opportunity Trial Reveals Mechanisms of Response and Resistance to Navtemadlin in Patients With Recurrent Glioblastoma. Sci Transl Med. 2025 Feb 19;17(786):eadn6274. PMID: 39970230. PMC11994224.

Vaidya K, Regan MS, Lin J, Houle J, Gupta A, Stopka SA, Agar NYR, Hammond PT, Boehnke N. Pooled Nanoparticle Screening Using a Chemical Barcoding Approach. Angew Chem Int Ed Engl. 2025 Jan 27;64(5):e202420052. PMID: 39714325. PMC11773315.

Shusharina N, Kaza E, Lam MB, Maier SE. Anatomy-Based Diffusion-Weighted MRI Quality Metric: A Proof-of-Concept for Deriving Accurate Muscle Fiber Orientation. Phys Med Biol. 2024 Dec 27;70(1). PMID: 39689675. PMC11784660.

Tobochnik S, Regan MS, Dorotan MKC, Reich D, Lapinskas E, Hossain MA, Stopka S, Meredith DM, Santagata S, Murphy MM, Arnaout O, Bi WL, Chiocca EA, Golby AJ, Mooney MA, Smith TR, Ligon KL, Wen PY, Agar NYR, Lee JW. Pilot Trial of Perampanel on Peritumoral Hyperexcitability in Newly Diagnosed High-grade Glioma. Clin Cancer Res. 2024 Dec 2;30(23):5365-5373. PMID: 39499201. PMC11611619.

Lan Z, Chen Y, Rushmore J, Zekelman L, Makris N, Rathi Y, Golby AJ, Zhang F, O’Donnell LJ. Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core. bioRxiv [Preprint]. 2024 Oct 22:2024.10.19.619237. PMID: 39484397. PMC11526951.

Margolis DJA, Chatterjee A, deSouza NM, Fedorov A, Fennessy FM, Maier SE, Obuchowski N, Punwani S, Purysko A, Rakow-Penner R, Shukla-Dave A, Tempany CM, Boss M, Malyarenko D. Quantitative Prostate MRI, From the AJR Special Series on Quantitative Imaging. AJR Am J Roentgenol. 2024 Oct 2. Review. PMID: 39356481. PMC11961719.

Epprecht L, Zekelman L, Reinshagen KL, Xie G, Norton I, Kikinis R, Makris N, Piccirelli M, Huber A, Lee DJ, Zhang F, O’Donnell LJ. Facial Nerve Tractography Using Diffusion MRI: A Comparison of Acquisition b-Values and Single- and Multifiber Tracking Strategies. Otol Neurotol. 2024 Oct 1;45(9):e647-e654. PMID: 39234825. PMC11458140.

Tan N, Pollock JR, Margolis DJA, Padhani AR, Tempany C, Woo S, Gorin MA. Management of Patients With a Negative Multiparametric Prostate MRI Examination: AJR Expert Panel Narrative Review. AJR Am J Roentgenol. 2024 Aug;223(2):e2329969. PMID: 37877601. PMC11407066.

Tripathi V, Rigolo L, Bracken BK, Galvin CP, Golby AJ, Tie Y, Somers DC. Utilizing Connectome Fingerprinting Functional MRI Models for Motor Activity Prediction in Presurgical Planning: A Feasibility Study. Hum Brain Mapp. 2024 Jul 15;45(10):e26764. PMID: 38994667. PMC11240144.

Juvekar P, Dorent R, Kögl F, Torio E, Barr C, Rigolo L, Galvin C, Jowkar N, Kazi A, Haouchine N, Cheema H, Navab N, Pieper S, Wells WM, Bi WL, Golby A, Frisken S, Kapur T. ReMIND: The Brain Resection Multimodal Imaging Database. Sci Data. 2024 May 14;11(1):494. PMID: 38744868. PMC11093985.

Chen Y, Zekelman LR, Zhang C, Xue T, Song Y, Makris N, Rathi Y, Golby AJ, Cai W, Zhang F, O’Donnell LJ. TractGeoNet: A Geometric Deep Learning Framework for Pointwise Analysis of Tract Microstructure to Predict Language Assessment Performance. Med Image Anal. 2024 May;94:103120. PMID: 38458095. PMC11016451.

Tobochnik S, Regan MS, Dorotan MKC, Reich D, Lapinskas E, Hossain MA, Stopka S, Santagata S, Murphy MM, Arnaout O, Bi WL, Antonio Chiocca E, Golby AJ, Mooney MA, Smith TR, Ligon KL, Wen PY, Agar NYR, Lee JW. Pilot Trial of Perampanel on Peritumoral Hyperexcitability and Clinical Outcomes in Newly Diagnosed High-Grade Glioma. medRxiv [Preprint]. 2024 Apr 18:2024.04.11.24305666. PMID: 38645003. PMC11030478.

Hwang GH, Pazyra-Murphy MF, Seo HS, Dhe-Paganon S, Stopka SA, DiPiazza M, Sutter N, Gero TW, Volkert A, Ombelets L, Dittemore G, Rees MG, Ronan MM, Roth JA, Agar NYR, Scott DA, Segal RA. A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer Res. 2024 15;84(6):872-886. PMID: 38486486. PMC10948029.

Zhu A, Tarasek M, Hua Y, Fiveland E, Maier SE, Mazaheri Y, Fung M, Westin CF, Yeo DTB, Szczepankiewicz F, Tempany C, Akin O, Foo TKF. Human Prostate MRI at Ultrahigh-performance Gradient: A Feasibility Study. Magn Reson Med. 2024 Feb;91(2):640-8. PMID: 37753628. PMC10841413.

Langbein BJ, Berk B, Bay C, Tuncali K, Martin N, Schostak M, Fennessy F, Tempany C, Kibel AS, Cole AP. A Phase II Prospective Blinded Trial of Magnetic Resonance Imaging and In-Bore Biopsy in Active Surveillance for Prostate Cancer. Urology. 2024 Jan 11:S0090-4295(23)01122-6. PMID: 38218388. PMC11161128.