Abstract Deep space exploration will cast unprecedented, multi-faceted health challenges for astronauts. The development of a non-invasive technique that can modulate region-specific brain activity may provide non-pharmacological alternatives for neurological/ psychological interventions for crew members undergoing long space missions. To…
Jeremy M Wolfe, PhD Professor of Ophthalmology & Radiology, Harvard Medical School Visual Attention Lab Department of Surgery, Brigham & Women's Hospital Abstract We cannot simultaneously recognize every object in our field of view. As a result, we deploy attention from…
Abstract Prostate cancer is the most commonly diagnosed cancer in men in the US. Diagnosis of prostate cancer is based on histological evaluation of tumor architecture using a system known as the ‘Gleason score’ and Gleason grade grouping. This diagnostic…
Yanmei Tie, PhD Assistant Professor of Neurosurgery Department of Neurosurgery Brigham and Women's Hospital Harvard Medical School Abstract In this study, we aim to assess the feasibility of using a movie-watching functional magnetic resonance imaging (fMRI) paradigm to extract the…
Abstract Transrectal ultrasound guided prostate biopsy (TRUSgBX) is a common diagnostic test for prostate cancer in the setting of an abnormal digital rectal examination or elevated prostate specific antigen. While TRUSgBX is known to have significant limitations, multiparametric MRI guided…
Abstract Noninvasive mechanical brain stimulation in the form of Pulsed Low-Intensity Focused Ultrasound (PLIFU) has recently shown promise as a neuromodulation method. PLIFU may serve as a treatment option for neurological disorders such as epilepsy or depression. A custom device platform and…
Abstract Recent breakthroughs enabling the hyperpolarization of biologically interesting compounds containing 13C are revolutionizing the ways we image metabolism in vivo. Unlike positron-emission tomography (PET), hyperpolarized 13C magnetic resonance (MR) spectroscopic imaging not only detects the injected 13C-labeled metabolite but also its downstream products…
Sandro Santagata, MD, PhD Associate Pathologist Brigham and Women's Hospital Assistant Professor of Pathology Harvard Medical School Abstract Brain tumors are a heterogeneous group of neoplasms driven by mutations in a wide array of tumor suppressor genes and oncogenes. Characterizing…
Khalid Shah, MS, PhD Director, Center for Stem Cell Therapeutics and Imaging Vice Chair of Research, Department of Neurosurgery Brigham and Women’s Hospital Associate Professor, Harvard Medical School Principal Faculty Harvard Stem Cell Institute Short Bio Khalid is an Associate…