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AT-NCIGT - The National Center for Advanced Technologies for Image Guided Therapy

Yanmei Tie, PhD: Pre-surgical Language Mapping in Brain Tumor Patients using Movie-watching fMRI

Yanmei Tie

Yanmei Tie, PhD
Assistant Professor of Neurosurgery
Department of Neurosurgery
Brigham and Women’s Hospital
Harvard Medical School


In this study, we aim to assess the feasibility of using a movie-watching functional magnetic resonance imaging (fMRI) paradigm to extract the language network in brain tumor patients.

Short Bio

Yanmei is an Assistant Professor of Neurosurgery at Brigham and Women’s Hospital (BWH) and Harvard Medical School (HMS). She has conducted original research in the fields of biomedical signal and image processing, neuroimaging, and neural engineering since graduation from college. After obtaining her PhD degree in Biomedical Engineering from Louisiana Tech University, Yanmei received postdoctoral training in neuroimaging and cognitive neuroscience in the Departments of Neurosurgery and Radiology at BWH. Yanmei’s research endeavors focus on improving presurgical brain mapping using multimodal MRI techniques, particularly functional MRI (fMRI). She has over 12 years’ experience in fMRI paradigm development, data analysis, validation against gold-standard tests, and evaluation with respect to patients’ outcome. Yanmei has led the effort of developing easy fMRI paradigms for language mapping for the patients who cannot perform task-based fMRI due to neurologic deficits. Her research interests also include using resting-state fMRI to study neural mechanism and develop neuroimaging biomarkers for a variety of neurological disorders.

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