Ferenc Jolesz First Monday Research Seminars
The Department of Radiology holds a monthly Ferenc Jolesz Seminar series presented by Harvard Medical School investigators, as well as speakers from other institutions, on a wide range of topics related to image-guided therapy. These seminars honor the late FERENC JOLESZ, MD who founded the multidisciplinary image-guided therapy program at Brigham and Women’s Hospital and is widely known as a founding father of the field of image-guided therapy.
Elizabeth Randall, PhD: Molecular Characterization of Prostate Cancer and Gleason Score using Mass Spectrometry Imaging
Abstract Prostate cancer is the most commonly diagnosed cancer in men in the US. Diagnosis of prostate cancer is based on histological evaluation of tumor architecture using a system known as the ‘Gleason score’ and Gleason grade grouping. This diagnostic…
Yanmei Tie, PhD: Pre-surgical Language Mapping in Brain Tumor Patients using Movie-watching fMRI
Yanmei Tie, PhD Assistant Professor of Neurosurgery Department of Neurosurgery Brigham and Women's Hospital Harvard Medical School Abstract In this study, we aim to assess the feasibility of using a movie-watching functional magnetic resonance imaging (fMRI) paradigm to extract the…
Alireza Ziaei-Torbati, MD: The Role of PIRADS V2 and TRUSgBX for Improving Detection of Clinically Significant Prostate Cancer at Radical Prostatectomy
Abstract Transrectal ultrasound guided prostate biopsy (TRUSgBX) is a common diagnostic test for prostate cancer in the setting of an abnormal digital rectal examination or elevated prostate specific antigen. While TRUSgBX is known to have significant limitations, multiparametric MRI guided…
Spencer Brinker, PhD: Neuronavigation-Guided Focused Ultrasound System for Delivering Mechanical Stimulation to Brain: Initial Developments
Abstract Noninvasive mechanical brain stimulation in the form of Pulsed Low-Intensity Focused Ultrasound (PLIFU) has recently shown promise as a neuromodulation method. PLIFU may serve as a treatment option for neurological disorders such as epilepsy or depression. A custom device platform and…
Yi-Fen Yen, PhD: Hyperpolarized 13C Metabolic Imaging of Prostate Cancer
Abstract Recent breakthroughs enabling the hyperpolarization of biologically interesting compounds containing 13C are revolutionizing the ways we image metabolism in vivo. Unlike positron-emission tomography (PET), hyperpolarized 13C magnetic resonance (MR) spectroscopic imaging not only detects the injected 13C-labeled metabolite but also its downstream products…
Sandro Santagata, MD, PhD: Advancing the Diagnosis and Treatment of Brain Tumors
Sandro Santagata, MD, PhD Associate Pathologist Brigham and Women's Hospital Assistant Professor of Pathology Harvard Medical School Abstract Brain tumors are a heterogeneous group of neoplasms driven by mutations in a wide array of tumor suppressor genes and oncogenes. Characterizing…
Khalid Shah, MS, PhD: Cell Based Therapies for Cancer: Are We There Yet?
Khalid Shah, MS, PhD Director, Center for Stem Cell Therapeutics and Imaging Vice Chair of Research, Department of Neurosurgery Brigham and Women’s Hospital Associate Professor, Harvard Medical School Principal Faculty Harvard Stem Cell Institute Short Bio Khalid is an Associate…
Oliver Jonas, PhD: An Engineering Approach to Precision Medicine using Implantable Microdevices
Oliver Jonas, PhD Director of the Laboratory for Bio-Micro Devices Brigham & Women’s Hospital Assistant Professor of Radiology Department of Radiology Brigham & Women’s Hospital Medical Oncology Dana-Farber Cancer Institute Abstract Precision medicine for human disease will require new tools…
Ronald Summers MD, PhD: The Impact of Deep Learning on Radiology
Ronald Summers MD, PhD Senior Investigator and Staff Radiologist Chief, Clinical Image Processing Service Chief, Imaging Biomarkers and Computer-Aided Diagnosis Laboratory Radiology and Imaging Sciences National Institutes of Health Clinical Center Abstract Building upon major advances in computer science, there…
Mark Michalski, MD: Machine Learning in the Healthcare Enterprise
Mark Michalski, MD Executive Director MGH and BWH Center for Clinical Data Science Abstract Machine learning is an emerging technology with promise to impact a wide variety of areas throughout the healthcare enterprise. In this discussion, we’ll review advances in…
Martha Shenton, PhD: Imaging in CTE and Repetitive Head Trauma
Martha Shenton, PhD Professor, Departments of Psychiatry and Radiology, BWH, HMS Director of the Psychiatry Neuroimaging Laboratory, BWH Health Scientist at the VA Boston Healthcare System, Brockton Division Senior Scientist, BWH Senior Scientist at The Judge Baker Children’s Center Research…