The Publication Database hosted by SPL
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Transperineal Magnetic Resonance Image Guided Prostate Biopsy
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Institution: |
Departments of Radiation Oncology, Radiology, Pathology and Urology, Brigham and Women’s Hospital, Boston, MA, USA. |
Publisher: |
J Urol |
Publication Date: |
Aug-2000 |
Volume Number: |
164 |
Issue Number: |
2 |
Citation: |
J Urol. 2000 Aug;164(2):385-7. |
PubMed ID: |
10893591 |
Keywords: |
Prostate, Prostatic neoplasms, Prostate-specific antigen, Magnetic Resonance Imaging, Biopsy |
Appears in Collections: |
SPL, NCIGT, Prostate Group, SLICER, SNR |
Generated Citation: |
D'Amico A.V., Tempany C.M., Cormack R., Hata N., Jinzaki M., Tuncali K., Weinstein M., Richie J.P. Transperineal Magnetic Resonance Image Guided Prostate Biopsy. J Urol. 2000 Aug;164(2):385-7. PMID: 10893591. |
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We report the findings of a transperineal magnetic resonance image (MRI) guided biopsy of the prostate in a man with increasing prostate specific antigen who was not a candidate for a transrectal ultrasound guided biopsy. Materials and Methods: Using an open configuration 0.5 Tesla MRI scanner and pelvic coil, a random sextant sample was obtained under real time MRI guidance from the peripheral zone of the prostate gland as well as a single core from each MRI defined lesion. The patient had previously undergone proctocolectomy for ulcerative colitis and, therefore, was not a candidate for transrectal ultrasound guided biopsy. Prior attempts to make the diagnosis of prostate cancer using a transurethral approach were unsuccessful. Results: The random sextant samples contained benign prostatic hyperplasia, whereas Gleason grade 3 + 3 = 6 adenocarcinoma was confirmed in 15%and 25%of the 2 cores obtained from the MRI targeted specimens of 2 defined lesions. The procedure was well tolerated by the patient. Conclusions: Transperineal MRI guided biopsy is a new technique that may be useful in detecting prostate cancer in men with increasing prostate specific antigen who are not candidates for transrectal ultrasound guided biopsy.
Additional Material
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