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A Computer-Controlled Ultrasound Pulser-Receiver System for Transkull Fluid Detection using a Shear Wave Transmission Technique

Institution:
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. sct@bwh.harvard.edu
Publisher:
IEEE Trans Ultrason Ferroelectr Freq Control
Publication Date:
Sep-2007
Volume Number:
54
Issue Number:
9
Pages:
1772-1783
Citation:
IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Sep;54(9):1772-83.
PubMed ID:
17941383
PMCID:
PMC2186207
Appears in Collections:
FUS, NCIGT
Sponsors:
R21 EB004353 (EB) funded by United States NIBIB
U41 RR019703 (RR) funded by United States NCRR
Generated Citation:
Tang S.C., Clement G.T., Hynynen K. A Computer-Controlled Ultrasound Pulser-Receiver System for Transkull Fluid Detection using a Shear Wave Transmission Technique. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Sep;54(9):1772-83. PMID: 17941383. PMCID: PMC2186207.
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The purpose of this study was to evaluate the performance of a computer-controlled ultrasound pulser-receiver system incorporating a shear mode technique for transskull fluid detection. The presence of fluid in the sinuses of an ex vivo human skull was examined using a pulse-echo method by transmitting an ultrasound beam through the maxilla bone toward the back wall on the other side of the sinus cavity. The pulser was programmed to generate bipolar pulse trains with 5 cycles at a frequency of 1 MHz, repetition frequency of about 20 Hz, and amplitude of 100 V to drive a 1-MHz piezoelectric transducer. Shear and longitudinal waves in the maxilla bone were produced by adjusting the bone surface incident angle to 45 degrees and 0 degrees, respectively. Computer tomography (CT) scans of the skull were performed to verify the ultrasound experiment. Using the shear mode technique, the echo waveform clearly distinguishes the presence of fluid, and the estimated distance of the ultrasound traveled in the sinus is consistent with the measurement from the CT images. Contrarily, using the longitudinal mode, no detectable back wall echo was observed under the same conditions. As a conclusion, this study demonstrated that the proposed pulser-receiver system with the shear mode technique is promising for transskull fluid detecting, such as mucus in a sinus.

Additional Material
1 File (329.19kB)
Tang-IEEE-TransUltrasonFerroelectrFreqControl2007-fig11.jpg (329.19kB)